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Orofacial Pain

Diagnosis

Made on the basis of a detailed assessment of the character of the pain, including: duration, site, severity, character, frequency and periodicity, associated features, initiating factors and relieving factors.

 

Neurological

Trigeminal Neuralgia

¨ unilateral, stabbing, electric-shock like pain in trigeminal nerve distribution – (1 or more of main branches)

¨ often trigger point identified by patient, lasts seconds

¨ pain intensity severe

¨ 50-70 years (<40 consider other cause)

¨ short duration only

¨ no neurological deficit

¨ idiopathic - ? compression around trigeminal nerve in posterior cranial fossa

 

Rx. - Carbamazepine used successfully for most – need regular blood tests

¨ (* hyponatraemia; suppresses WBC, RBC, Plts; induces liver enzymes)

¨ other anticonvulsants or antidepressants can be used

¨ peripheral nerve techniques eg cryosurgery, glycerol injections, thermocoagulation

¨ central neurosurgery for intractable cases (microvascular decompression)

 

Glossopharyngeal Neuralgia

¨ much less common than trigeminal neuralgia

¨ pain of a similar nature but affects tonsil, oropharynx and/ or ear

¨ triggered by swallowing or coughing

 

Rx. – Carbamazepine less effective, Gabapentin also used

¨ usually secondary to lesions in post. cranial fossa or jugular foramen

 

Herpes zoster (including post-herpetic neuralgia)

¨ neuralgia both precedes and accompanies shingles

¨ 10% of pts who have had recurrent VZV develop neuralgia during acute phase and persisting (post-herpetic) more than 6 months afterwards, elderly mostly

¨ post-herpetic neuralgia can be extremely resistant to Rx., pain can be intolerable, analgesics rarely effective, anti-depressants and anti-convulsants can help

 

Vascular

Migrainous Neuralgia (Cluster Headache)

¨ oedema and dilatation of walls of internal carotid artery and possibly external also

¨ 30-50 years, more common in men

¨ retro-orbital excruciatingly severe ‘boring’ pain, lasts less than an hour

¨ pain onset and termination is sudden

¨ precipitated by alcohol, or occurs spontaneously 1-3 times/day

¨ obvious vascular changes associated: lacrimation, nasal congestion and/or rhinorrhoea

¨ no visual symptoms, nausea or vomiting associated as a migraine
Rx. oxygen and sumatriptan

¨ Prophylaxis with verapamil, lithium, nifedipine, diltiazem

 

Giant cell arteritis

¨ granulomatous vasculitis of vessels in head and neck

¨ over 60 years

¨ unilateral ‘headache-like’ pain (severe dull ache) in temporal/occipital region

¨ systemic upset: weight loss, muscle weakness, lethargy

¨ temporal artery frequently becomes red, swollen, firm, tender and tortuous
ESR usually raised, possibly CRP also (ESR reasonable guide to disease activity)

¨ temporal artery biopsy useful in confirming diagnosis (>3cm length as skip lesions)

¨ risk of blindness due to retinal vasculitis

¨ start oral prednisolone ASAP (60mg/day), good response if treated early

 

Psychogenic

Atypical facial pain

¨ chronic pain of unknown aetiology

¨ 50% of pts. have anxiety or depression associated

¨ often women middle-aged or older

¨ absence of organic signs

¨ pain poorly localised, persists for many years on daily basis

¨ lack of response to analgesics, lack of triggering factors

¨ diagnosis made on basis of history and absence of dental cause for pain

¨ cranial nerve function should be assessed

¨ CT or MRI to exclude malignancy at base of skull

¨ Rx. responds well to anti-depressants

 

Burning mouth syndrome (oral dysaesthesia)

¨ aetiology uncertain

¨ no visible abnormality, organic disease or haematological abnormality

¨ middle-aged or older woman mainly affected

¨ burning pain, persistently sore

¨ bizarre patterns of pain inconsistent with neurological or vascular anatomy

¨ associated depression, anxiety, cancerophobic (20% of cases)

¨ obsession with symptoms may rule patients’ life

¨ Rx. involves reassurance of common nature and no serious underlying problem

¨ antidepressants help, sometimes dramatically

This is the main reason why patients attend a dental clinic.  In most cases, an obvious dental cause of the symptoms can be identified, and appropriate treatment provided.

 

A wide range of diseases apart from local disorders can cause oro-facial pain, including neurological, vascular and psychogenic causes.