|
Effects of drug treatments used in Neurological disorders |
|
¨ Gingival overgrowth is a recognised side effect of phenytoin but may also occur with sodium valproate and ethosuximide.
¨ In addition, phenytoin causes taste disturbance and may produce Stevens-Johnson syndrome. ¨ This drug may also affect the teeth. It has been implicated in producing hypercementosis and shortening of the roots.
¨ Sodium valproate may produce parotid gland enlargement.
¨ Lamotrigine may cause dry mouth and Stevens-Johnson syndrome.
¨ Ethosuximide may produce Stevens-Johnson syndrome and gingival bleeding.
¨ Carbamazepine may produce xerostomia, glossitis and oral ulceration.
¨ The anti-muscarinic anti-Parkinsonian drugs such as orphenadrine and benzhexol can produce dry mouth, which may increase caries incidence.
¨ In addition, the dopaminergic drugs such as levodopa and co-careldopa may produce taste disturbances.
REF: British Dental Journal 12 July 2003; Volume 195, No. 1
|
|
Drugs used to treat neurological conditions can produce unwanted effects in and around the mouth. Anticonvulsants have a number of unwanted effects of interest to dentists. |